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Ndemanga yaposachedwa yofalitsidwa ndi gulu lofufuza zasayansi ku Canada ikuwonetsa kuti cannabinoids atha kutengapo gawo popewa ndi kuchiza COVID-19 komanso COVID-19 yanthawi yayitali.

Pakuwunikanso mwatsatanetsatane, gulu la asayansi aku Canada limapereka zidziwitso zosangalatsa za gawo lomwe cannabinoids angagwire polimbana ndi kachilombo ka COVID-19.Kafukufukuyu, wotchedwa "Cannabinoids ndi Endocannabinoid System in Early SARS-CoV-2 and Chronic COVID-19 Patients," adalembedwa ndi Cassidy Scott, Stefan Hall, Juan Zhou, Christian Lehmann ndi ena ndipo adasindikizidwa mu Journal of SARS-CoV. -2 ″ magazini.

Clinical Medicine.Powunika zambiri zamaphunziro am'mbuyomu, lipotilo likufotokoza momwe zigawo za chomera cha cannabis zingatengere gawo lalikulu popewa kuyambika kwa COVID-19 ndikuchepetsa zotsatira zake zanthawi yayitali.Zomwe zapezazi zikuwonetsa kuti cannabinoids, makamaka omwe amachokera ku chomera cha cannabis, amatha kuletsa ma virus kulowa m'maselo, kuchepetsa kupsinjika koyipa kwa okosijeni, komanso kupondereza kuyankha kwamphamvu kwa chitetezo chamthupi komwe kumachitika nthawi zambiri.Kafukufukuyu akuwunikiranso gawo lomwe lingakhalepo la cannabinoids pothana ndi zizindikiro zosiyanasiyana za nthawi yayitali za COVID-19.

Malinga ndi kafukufukuyu, cannabinoids ali ndi kuthekera koletsa kulowa kwa ma virus, kuchepetsa kupsinjika kwa okosijeni komanso kuchepetsa mkuntho wa cytokine wokhudzana ndi kachilombo ka COVID-19.Kafukufuku akusonyeza zimenezimankhwala a cannabinoidimatha kuchepetsa kuchuluka kwa angiotensin-converting enzyme 2 (ACE2) m'matenda akuluakulu, motero kuletsa ma virus kulowa m'maselo amunthu.Ofufuzawo akuwona kuti izi ndizofunikira chifukwa cha udindo wa ACE2 ngati khomo lolowera ma virus.Lipotilo likukambirananso za ntchito ya cannabinoids pothana ndi kupsinjika kwa okosijeni, chinthu chofunikira kwambiri pa matenda a COVID-19.

Potembenuza ma radicals aulere kukhala mawonekedwe ocheperako, cannabinoids mongaCBDzitha kuthandiza kuchepetsa zowopsa za kupsinjika kwa okosijeni muzovuta kwambiri za COVID-19.Malinga ndi kafukufukuyu, cannabinoids atha kukhalanso ndi zotsatira zabwino pamikuntho ya cytokine, kuyankha kwakukulu kwa chitetezo chamthupi komwe kumayambitsidwa ndi COVID-19.Cannabinoids awonetsedwa kuti ndi othandiza kuchepetsa ma cytokines otupa, kutanthauza kuthekera kwawo pakuwongolera mayankho a chitetezo chamthupi.

COVID-19 yayitali imatanthawuza mkhalidwe womwe nthawi zambiri umachitika ngati kusintha kwa COVID-19 kupita ku gawo lokhazikika.Kafukufukuyu akuwonetsa kuthekera kwa cannabinoids pochiza zizindikiro za kukhumudwa, nkhawa, kupsinjika kwapambuyo pamavuto, kusowa tulo, kupweteka komanso kusowa kwa njala.Dongosolo la endocannabinoid limathandizira kulumikizana kwamachitidwe osiyanasiyana amanjenje, ndikupangitsa kuti ikhale chandamale chochizira zizindikiro za neuropsychiatric izi.

Kafukufukuyu adawunikiranso njira zosiyanasiyana zamagwiritsidwe ntchito komanso mitundu yosiyanasiyana yazinthu za cannabis zomwe ogula amagwiritsa ntchito.Kafukufuku akuwonetsa kuti kumeza kudzera pokoka mpweya kumatha kukhala ndi zotsatirapo zoyipa kwa anthu omwe ali ndi vuto la kupuma, zomwe zimatsutsana ndi machiritso ake."Ngakhale kusuta ndi kusuta nthawi zambiri kumakhala njira zomwe odwala a cannabis amakonda kwambiri chifukwa amafulumira kwambiri, mapindu omwe angakhalepo a cannabinoid mankhwala amatha kuthetsedwa ndi zotsatira zoyipa za kupuma paumoyo wa kupuma," ofufuzawo adatero.Kafukufuku akuwonetsa "Odwala omwe amagwiritsa ntchito cannabis vaporization amakhala ndi zizindikiro zochepa za kupuma kuposa kusuta fodya chifukwa chipangizo cha vaporizer sichimatenthetsa chamba mpaka kuyaka."Olemba lipotilo akutsindika kufunika kofufuza mowonjezereka m’derali.Ngakhale zomwe zapeza zoyambilira zili zolimbikitsa, amachenjeza kuti ndizoyambira ndipo zimachokera ku maphunziro omwe sanatchule COVID-19.Chifukwa chake, maphunziro omwe amayang'ana kwambiri komanso athunthu, kuphatikiza mayeso azachipatala, ndikofunikira kuti timvetsetse bwino ntchito ndi mphamvu ya cannabinoids pochiza matenda a SARS-CoV-2 oyambirira komanso owopsa.Kuphatikiza apo, olembawo amalimbikitsa kuti pakhale kafukufuku wozama pazamankhwala ndi njira zochiritsira zomwe zingachitike mu dongosolo la endocannabinoid ndikulimbikitsa asayansi kuti afufuze mozama njira iyi.